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What are short chain fatty acids (SCFA) and Butyrate?
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What are short chain fatty acids (SCFA) and Butyrate?

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What are short chain fatty acids (SCFA) and Butyrate?

Contribution to gut barrier function and maintenance.

Diet, type of food, Fibre-soluble and insoluble, Bacteria, Prebiotics, Probiotics, Yoghurts, Stomach acid, resistant starch, Inulin, FOS.

Short chain fatty acids (SCFA) are chemicals produced in the large bowel as a result of bacterial fermentation of soluble fibre and starch that cannot be broken down by human digestive enzymes (Resistant starch).

The main short chain fatty acids are Acetic acid, Propionic acid and Butyric acid.

The short chain fatty acids contribute towards a healthy colon and are important for the proper functioning of the immune system and the gut mucosal barrier.

The short chain fatty acids appear to have numerous functions in the running of the gastrointestinal tract. They are easily absorbed by the intestinal mucosa, which is the innermost lining of the intestines, and may be used as a source of energy by the cells lining the intestines and colon.

Butyric acid is known to be the preferred fuel source of the colonocytes (cells lining the inner lining of the colon). Acetic acid is used as a fuel by the muscles and propionic acid is metabolised by the liver.

Butyric acid or Butyrate appears to be the more important SCFA in the colon and is known to have multiple beneficial effects and plays an important role in the maintenance of intestinal health.

Research has shown that butyric acid has the following effects in the body:
1.Regulation of fluid and electrolyte uptake.
Absorption of butyric acid by the colonocytes promotes the transport of sodium chloride (salt) and water from the lumen into the bloodstream. This effect contributes towards electrolyte balance in the body. 
2. Effects on proliferation and differentiation of epithelial intestinal cells.
Butyrate has a positive effect on cell growth and cell differentiation and appears to stimulate the physiological pattern of cell division, leading to normalisation of tissue growth.
The anti cancer effect of fibre may be due to Butyrate production in the colon.
3.Butyrate has anti-inflammatory and anti-oxidant properties and may contribute positively towards the integrity of the intestinal mucosa.
The human colon is continually exposed to toxic substances and Butyrate may play a protective role in mucosal barrier function and the prevention of disease that may be stimulated by potential toxins and carcinogens in the colon.
4. Butyrate plays a role in reinforcing the intestinal defence barrier.
Butyrate stimulates the production of mucin by the colonocytes.
Mucin is essential for the synthesis of Mucus.
Mucus lines the lumen of the intestinal tract and provides lubrication and intestinal barrier defence against entry of harmful microbes and other material into the body.
Butyrate has an effect on intestinal epithelial permeability and regulates the colonic defence barrier by a mechanism that involves the assembly of
tight junctions in the epithelial lining.

An inflamed gastrointestinal lining has increased permeability (leaky gut) and will allow entry of substances from the lumen into the blood stream of food particles that may not be fully digested (especially proteins).
Other toxins and breakdown products of microbes that are normally selectively inhibited from entry may also pass into the bloodstream and produce an inflammatory reaction because the body recognises these proteins as “foreign” antigens. The inflammatory reactions may lead to local and systemic disease processes being triggered.

It is therefore important to ensure that the lining of the gastrointestinal tract is healthy and functioning at full capacity at all times and the integrity of the Barrier function is maintained so that only selective ingredients are allowed to pass through into the bloodstream from the lumen.
5.Butyrate increases colonic circular muscle contractions and modulates colonic motility. Enhanced production of Butyric acid in the colon by nutritional manipulation may be useful in medical conditions associated with impaired intestinal motility. (e.g. Irritable bowel syndrome)


How to heal and prevent Bowel disorders

Diet is not about what you should NOT eat, it’s about what you should include in the diet that matters.
As long as your diet includes the correct balance of plant foods containing soluble fibre, insoluble fibre and resistant starch your colon will produce the perfectly formed stool. The important next step is to evacuate this stool without straining so that the body does not suffer from the pressures created each time the bowel is emptied.

In order to heal and prevent bowel disorders you need to make lifestyle changes that last the rest of your life time.

1. Include more fluids and plant food containing soluble fibre, insoluble fibre and resistant starch in the diet so that the perfectly formed stool will be made in the colon and beneficial bacteria will flourish and eliminate disease causing bacteria and fungi.

2. Evacuate the perfectly formed stool by adopting the squat posture to eliminate the need to strain during bowel movements.

It is not possible or safe to squat on the modern raised toilet seat installed in all western homes and it is impossible to squat for any length of time if you have not done this from childhood onwards. This makes the use of any raised platforms impossible to adapt to.

The SquattLooStool is designed to allow you to adopt the squat posture while seated comfortably on your raised toilet seat.
The single best and easiest lifestyle change you will ever make, leading to a healthier body.


The ingredients necessary for the formation of the perfectly formed stool are a combination of soluble fibre, insoluble fibre and resistant starch in addition to your normal diet.

A suggested recipe that will help make a well formed stool and provide food for the friendly Bacteria in the Colon, allowing the local production of the health providing Butyric acid.

One RAW Potato............ wash, peel and dice the potato, make sure there are no GREEN or BLACK spots on the potato. You only need the white or yellow flesh. Choose a high starch content or Floury Potato for best results

One RAW Carrot peeled and diced

One Apple washed and diced (no need to peel)

One Beet Root, diced (not pickled—avoids Vinegar)

One small piece of Ginger root or half a teaspoonful of dried Ginger powder

Half a Lemon (peeled)

Half a Lime (peeled)

Liquidize the ingredients in a food processor. Add water or Fruit juice to thin down into a juice.

Drink one large Glassful daily.

This Raw Vegetable juice will introduce soluble fibre, Insoluble fibre and Resistant Starch without much effort into your diet and provide the ingredients that will lead to a healthier Colon.

Colon healthy optional extras you can add to the juice to fortify it with other health providing ingredients.

One tablespoon of Barley malt extract
One tablespoon of Inulin powder
One tablespoon of cracked Flax or Linseeds
One tablespoon of Chia seeds
One teaspoon of Basil seed
One tablespoon of Raw Potato Starch

Always add these ingredients to the COLD juice or Water.
Heat will destroy the health providing starch and fibre ingredients of the chosen materials.